Disney said in a statement: “Fans have a sentimental attachment to Lizzie McGuire and high expectations for a new series.
“After filming two episodes, we concluded that we need to move in a different creative direction and are putting a new lens on the show.”
Minsky’s replacement has not been announced. Duff, 32, is currently on her honeymoon with her new husband Matthew Koma.
The original series of Lizzie McGuire ran for two seasons between 2001 and 2004 and followed the life of a 13-year-old girl navigating her way through school and adolescence.
The new series will see Lizzie, now approaching 30, living in New York working as an assistant to an interior decorator.
Adam Lamberg, who played Lizzie’s best friend Gordo, is also set to return.
Lizzie McGuire creator stands down from show’s Disney+ reboot