A £4million refurbishment of the neuroscience ward at Aberdeen Royal Infirmary will get under way later this month.
Upgrade work was due to begin last summer but put back until this year.
In addition to the NHS Grampian funds, Friends of the Neuro Ward-ARI (FNWA) will contribute £125,000 to the revamp.
Orkney-based charity founder Caroline Critchlow said the money would be used to renovate the day room and create a separate Orkney and Shetland Respite Room.
It will be a space where patients can wait while their relatives are in the operating theatre and meet consultants.
The donation will also go towards transforming the bathrooms into accessible wet rooms and providing the high dependency unit (HDU) with its own toilet.
This will mean patients no longer have to use a commode in the mixed ward.
Additionally, the Press and Journal understands the stroke ward is moving, enabling expansion of the neuro-ward.
Ms Critchlow, 57, whose husband Kevin’s brain tumour was successfully operated on at the hospital four years ago, said she was relieved the work would be starting.
She said: “It’s so brilliant talking to the staff because their spirits have lifted so much. The whole mood on the ward has changed.
“From my point of view, I’ve put so much emotional energy into this.
“It’s been four years since Kevin’s operation. It could not be a better anniversary present.”
In total, the charity has raised more than £250,000, some of which has already been spent on a motorised shower trolley – so patients can shower as soon as they come out of theatre – and a machine that measures the recovery of the facial nerve.
Some £50,000 will be spent on a virtual protein reveal imaging machine which allows surgeons to look at brain scans in 3D.
The charity is currently taking advice on which model to buy, but hopes to move ahead with the purchase soon after the refurbishment.
It also continues to fundraise, setting its future sights on providing four new beds with the latest monitoring equipment and a nurses station for the HDU.
Ms Critchlow said this would help alleviate the pressure on intensive care.
An NHS Grampian spokeswoman said the refurbishment was part of a rolling programme of improvement at the hospital.
She added: “Generous donations received from supporting charities and the local community will supplement the refurbishment of the neuro ward.”
The work will begin on April 29.