Emergency services were in attendance at the scene for several hours with the road closed in both directions between Garthdee and Maryculter.
A fire service spokeswoman confirmed two appliances had been dispatched from Central and Altens fire stations. Both crews left the scene at 5pm.
Police has now confirmed three people have been taken to Aberdeen Royal Infirmary following the crash.
The road was closed for around five hours before eventually reopening at 8pm.
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Three people taken to hospital following two-car crash near Ardoe House Hotel
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