Mannofield, the home of Aberdeenshire CC, last hosted internationals three years ago when Oman and Papua New Guinea were Scotland’s opposition.
Aberdeenshire president Willie Donald said: “The arrival of two strong teams from the USA and UAE will provide excellent opposition to our equally strong Scotland squad.
“We expect great interest in the six one-day internationals given Aberdeen’s long and deep relationships with both the USA and UAE.
“With all three teams fighting for qualification for the 2023 World Cup, we expect fireworks on the field.”
Finishing in the top three in World Cup League 2 will secure a place at the 2023 World Cup qualifier for the Scots.